Im using this for flight simulators and it works pretty good:
3x BenQ 24" LCD G2420HD
3x Evga 570 gtx Super clocked
Corsair Vengeance DDR3 1866MHz 32GB CL10
EVGA Z68 FTW E-ATX
Intel Core i7 3770K 3,5Ghz
Saitek X52 pro
This setup works pretty well with DCS games - but I havent tried it with X-plane 10 yet since I cannot find the dvd 
shitloads of new stuff in my pc. Cant keep track of it all.