Been an ATI user for a long time(ok,bought 8800 GTX at one point,but other than that) and never had any serious issues.
But congrats...it's an awesome card.
I only had to enable the second GPU manually via device manager since it wouldn't go to crossfire by default.
AMD Ryzen 9 7900X 4,7 GHz
Asrock X670E Steel Legend
G.Skill Trident Z5 32 GB DDR5 6400Mhz
Asus TUF RTX 4090 24 GB GDDR6X
NZXT Kraken Z73 RGB
Corsair HX1500i Platinum
NZXT H7 Flow